Some reactions of 10-substituted-10H-pyrido[3,2-b][1,4]benzothiazine-n-butyllithium adducts with acyl and sulfonyl chlorides
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منابع مشابه
Synthesis of N-Sulfonyl Amidines and Acyl Sulfonyl Ureas from Sulfonyl Azides, Carbon Monoxide, and Amides.
A Pd-catalyzed and ligand-free carbonylation/cycloaddition/decarboxylation cascade synthesis of sulfonyl amidines from sulfonyl azides and substituted amides at low CO pressure is reported. The reaction proceeds via an initial Pd-catalyzed carbonylative generation of sulfonyl isocyanates from sulfonyl azides, followed by a [2 + 2] cycloaddition with amides and subsequent decarboxylation, which ...
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Acylation reaction of a variety of cyclic ketones via acylation of the corresponding enamines is welldefined in the literature. Enamine acylation of carbonyl compounds is a significant synthetic method because of its mildness and the ease of preparing various β-diketones [1-4]. Acylation reactions are performed by means of converting enamines to the enaminoketones and subsequent hydrolysis of t...
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Some N¬-acyl-N'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. The structures of synthesized compounds have been characterized by IR, 1HNMR spectral studies. The synthesized compounds 5(a-f) have been screened for antibacterial activity. The effect of the structure of the investigated compounds on the antibacterial activ...
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Carbon–carbon cross-coupling reactions are very important in the areas of material science and medicinal chemistry. Most current methods require expensive transition-metal catalysts (for example, based on Cu, Pd, Co, Ni, Pt, Ru, and Rh) and ligands (for example, phosphines). Early reports by Kharasch and Reinmuth in 1954 and then by Tamura and Kochi in 1971 suggested that inexpensive Grignard r...
متن کاملBase-catalyzed cyclization of N-sulfonyl propargylamides to sulfonylmethyl-substituted oxazoles via sulfonyl migration.
The reaction of N-sulfonyl propargylamides in the presence of a base catalyst selectively affords 5-sulfonylmethyl oxazoles via 1,4-sulfonyl migration. Allenes have been established as the key intermediates. Experimental evidence has been provided to support a two-step mechanism in the cyclization.
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1979
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v79-381